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Hongbing Liu, PhD

Impact of biological sex on chronic kidney disease and kidney cancer


Dr. Liu’s research focuses on the epigenetic regulation of kidney development and disease. The long-term goal of his research program is to uncover the epigenetic mechanisms, especially histone acetylation and deacetylation, responsible for kidney formation and abnormality. The ongoing projects in Dr. Liu’s lab are: 1) The regulation of renal development by histone deacetylases; 2) The roles of histone deacetylases in Wilms tumors; and 3) Epigenetic reprogramming of chronic kidney disease. Biological sex contributes significantly to chronic kidney disease and kidney cancer. Sex is included as a biological variable in all ongoing studies in Dr. Liu’s lab.

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